Janus kinase inhibitors - holistically seeing two faces
نویسندگان
چکیده
منابع مشابه
Advances in the Inhibitors of Janus Kinase
In recent years, for the lesion site, studies at the molecular level of drugs targeting protein molecules has been a major research method for exploiting new, high-efficiency drugs with low toxicity [1]. Janus kinases (JAKs) are important signal transducers of many cytokines, growth factors and interferon. In recent years, it has been found in cancer cells and cells transfected with oncogenes t...
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The reports of a unique mutation in the Janus kinase-2 gene (JAK2) in polycythemia vera by several independent groups in 2005 quickly spurred the development of the Janus kinase inhibitors. In one of the great victories of translational research in recent times, the first smallmolecule Janus kinase inhibitor ruxolitinib entered a phase I trial in 2007. With the approval of ruxolitinib by the US...
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Face inversion effects are used as evidence that faces are processed differently from objects. Nevertheless, there is debate about whether processing differences between upright and inverted faces are qualitative or quantitative. We present two experiments comparing holistic processing of upright and inverted faces within the composite task, which requires participants to match one half of a te...
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The neural mechanisms responsible for triggering visual hallucinations are poorly understood. Here, we report a unique patient whose hallucinations consist exclusively of faces, and which could be reliably precipitated by looking at trees. Using functional Magnetic Resonance Imaging (fMRI), we found that, while face hallucinations was associated with increased neural activity in a number of cor...
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Holistic processing is considered one of the hallmarks of face recognition. Recent studies using the composite task claim to show a lack of holistic processing for dynamic faces, however they only presented moving faces in the learning phase and tested with static composite images. So while previous research has addressed the question of whether moving faces influence the processing of subseque...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2015
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.2015.006